However, the DNA methylation levels of DNMT3A, DNMT3B, MBD1, MBD2, MBD3, MBD4, ZBTB33, ZBTB38, ZBTB4, UHRF1, UHRF2, MECP2, NTHL1, TET1, TET2, and TWT3 significantly differed between paracancerous and PCa tissues (Wilcoxon test: P < 0.05; Figure 1(e)). This evidence concerns the gene MBD1 and posterior cortical atrophy.