However, the DNA methylation levels of DNMT3A, DNMT3B, MBD1, MBD2, MBD3, MBD4, ZBTB33, ZBTB38, ZBTB4, UHRF1, UHRF2, MECP2, NTHL1, TET1, TET2, and TWT3 significantly differed between paracancerous and PCa tissues (Wilcoxon test: P < 0.05; Figure 1(e)). The gene discussed is NTHL1; the disease is posterior cortical atrophy.