SOAT1 and cancer: It is suggested to be also involved in cancer development by mediating the Janus kinase/signal transducers and activators of transcription (JAK/STAT) cascade pathway (Mullen and Gonzalez-Perez, 2016), which induces proliferation and angiogenesis of cancer cells (Mullen and Gonzalez-Perez, 2016; Wang et al., 2018) and regulates the immune responses to tumors (Zhang et al., 2020a).