Modeling of network modules by cluster analysis, associated X-ALD with the ABCD1-3 and PEX19 network motif, whereas PEX26 was grouped with all phenotypes of the Zellweger spectrum and phenotypes of deficient peroxisomal fission (PEX11B and DNM1L deficiency). This evidence concerns the gene PEX11B and X-linked adrenoleukodystrophy.