The 29942092_rm is comprised of the differentially expressed genes of a tissue-resident memory T (TRM) cell cluster in breast cancer (8), the 28930685_rm is a core transcriptional and phenotypic signature which defines human tissue-resident memory for both CD4+ and CD8+ T cells (59), and the 31359002_act is a T cell activation signature, which consisted of the top 50 genes correlated with IFNG (60). The gene discussed is CD4; the disease is breast cancer.