LINC-PINT and rheumatoid arthritis: Downregulated lncRNAs LINC-PINT, LINC01197, and OIP5-AS1 in RA synovial tissue lead to increased levels of their respective targets miR-155, miR-150, and miR-448 in RA FLS, which in turn lead to cell proliferation, invasion, and inflammatory responses (35–37).