TNF and atherosclerosis: Treatment with TNF-α inhibitors in psoriasis patients could reverse early atherosclerosis at the initial stage presented as significantly reduced arterial intima-media thickness (IMT) values without irreversible atherosclerotic plaque (which indicates the development of subclinical atherosclerosis) and decreased signal intensity on β-2-(18F)-fluoro-2-deoxy-D-glucose-Positron emission tomography/computed tomography (FDG-PET/CT), implying less vascular inflammation (Jókai et al., 2013; Dey et al., 2017).