TGFB1 and Hepatic fibrosis: The evidence has shown that Forsythiae Fructuse water extract (FSE), Curcuma Wenyujin, and Zingiber Officinale can effectively inhibit the development of liver fibrosis through the TGF-β/Smads signaling pathway (Hasan et al., 2016; Hu et al., 2020a; Xie et al., 2020).