Consistent with findings from human patients and mouse models of ALI (Saetta et al., 2002; Petty et al., 2007; Hartl et al., 2008; Costello et al., 2012; Ichikawa et al., 2013; Ngamsri et al., 2017; Liao et al., 2020), in this study using LPS-challenged DBA/1 mice, CXCR3 and CXCR4 ligands were elevated in the BAL, which was associated with increased BAL CXCR3+ and CXCR4+ cell infiltrates. The gene discussed is CXCR4; the disease is acute respiratory distress syndrome.