PLAT and Stroke: Unfortunately, intravenously recombinant tissue plasminogen activator (rtPA) is so far the only Food and Drug Administration (FDA)-approved thrombolytic agent for treating ischemia stroke within the golden hour 4.5 h of stroke onset (National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group., 1995; Sandercock et al., 2012).