Among these bioactive components, the top five degree components associated with multiple ARDS targets include histidine decarboxylase (MOL4480, degree = 18), androgen receptor (MOL422, degree = 11), telomerase protein component 1 (MOL675, degree = 10), amine oxidase B (MOL 1801, degree = 9), nitric-oxide synthase (MOL 1893, degree = 6). The gene discussed is HDC; the disease is acute respiratory distress syndrome.