GPT and systemic inflammatory response syndrome: Studies also suggest that Atractylodes lactone I can limit the levels of inflammatory cytokines (TNF-α, IL-6, and IL-1β), alanine transaminase (ALT), aspartate transaminase (AST), creatinine (CRE), and blood urea nitrogen (BUN), can improve sepsis syndrome, and can improve kidney function (Wang A. et al, 2016).