In heart failure patients (left ventricular ejection fraction 18 ± 8%, NYHA classes III-IV), the plasma SST concentration was found to be around 18 pmol/l (Deis et al., 2020), which is a similar range found in our present study in porcine plasma showing that human and the porcine plasma SST level might be in the same range. Here, SST is linked to heart failure.