Finally, since c-Fos has been suggested as an indicator of neuronal plasticity (Jaworski et al., 2018), the results of the present research showed that maternal separation can affect the plastic capacity of several brain nuclei, which constitute a physiological basis for the emergence of behavioral disorders presented later in life reported to be linked to early life adversity (Costello et al., 2003; Green et al., 2010; Girardi et al., 2014; Birn et al., 2017). Here, FOS is linked to Atypical behavior.