Basigin has been implicated in diverse biological processes in vertebrates and invertebrates from embryonic membrane apposition (Reed et al., 2004), embryo implantation (Igakura et al., 1998), tumor invasion (Muramatsu and Miyauchi, 2003), synapse formation (Besse et al., 2007), to cell surface localization of lactate transporters (Kirk et al., 2000). Here, BSG is linked to neoplasm.