The outgrowth of bipolar cell dendrites was reported to be observed under some pathologic conditions, such as retinal detachment (Fisher et al., 2005), the nob2 mouse with a calcium channel Cav1.4 null mutation (Bayley and Morgans, 2007) and Bsn mice lacking functional Bassoon protein (Dick et al., 2003). This evidence concerns the gene CACNA1F and retinal detachment.