The enrichment analysis of DEGs showed 5 KEGG pathways were related to the development and progress of TB, including ‘hepatocellular carcinoma,' ‘Kaposi sarcoma-associated herpesvirus infection,' ‘phosphatidylinositol signaling system,' ‘circadian entrainment,' and ‘apelin signaling pathway.' A protein-protein interaction (PPI) network of DEGs and DEGs-DE miRNAs was created.10 hub genes were then chosen. This evidence concerns the gene APLN and tuberculosis.