However, the up-expression of circ-PTPDC1 was positively correlated with age, T stage and clinical stage (p<0.05) (Table 1). In addition, univariate and multivariate analysis indicated that circ-PTPDC1 expression level, TNM stage and invasion depth were independent prognostic indicators of OS and DFS in GC patients (Table 2). The gene discussed is PTPDC1; the disease is gastric cancer.