PTPDC1 and gastric cancer: Interestingly, the results showed that the AUC of circ-PTPDC1 expression in advanced (III-IV) TNM stages of GC was 0.809, higher than 0.539 in early (I-II) TNM stages (Fig. 10G). Taken together, dysregulated circ-PTPDC1 may serve as a key regulatory factor or prognostic biomarker of GC.