In addition, over-expression ofthe intracellular domain of the Notch1 receptor (N1IC) enhances the development of gastric cancer, including tumour formation, metastasis, migration and invasion, by facilitating the intercellular interplay of STAT3 and the promoter of Twist [10].Attention to Andrographis paniculata Nees, a well-known plant from the traditional Indian and Chinese medicinal systems is gaining [11]. This evidence concerns the gene STAT3 and gastric cancer.