Targeted therapies with anti-epidermal growth factor receptor have also been tried for CRC [10].Despite significant clinical management involving targeted therapies, chemo/radiotherapies, and surgical procedures, CRC remains one of the frequent causes for cancer-related death worldwide and it is cause for concern [11].Further, chemo/radiotherapy is responsible for off-target side effects like nausea, vomiting, diarrhea, mucositis with taste alteration, alopecia, constipation, fatigue, anorexia, sleep disturbance, headache, anemia and dry skin [12-13]. The gene discussed is EGFR; the disease is colorectal carcinoma.