EPHX2 and nervous system disorder: The inhibition of sEH has a plethora of beneficial central effects, such as reducing inflammation, endoplasmic reticulum (ER) stress, oxidative stress markers, tau pathology, and the amyloid burden.[52] Besides peripheral inflammatory‐related diseases, inhibition of inflammation in the brain by targeting sEH was found to be a relevant therapeutic strategy for several psychiatric and neurological disorders.[64, 65]