Among them, the adamantyl group used in N‐adamantanyl‐N'‐dodecanoic acid urea (AUDA) and 1‐adamantan‐3‐(5‐(2‐(2‐ethylethoxy)ethoxy)pentyl)urea yielded exceptionally high potency on the target sEH.[88] AUDA could rescue the inhibition of proliferation and increased expression of Tumour Necrosis Factor alpha (TNF‐α), Interleukin‐1 beta (IL‐1β), Matrix Metalloproteinase‐9 (MMP‐9 induced by Kawasaki disease sera. This evidence concerns the gene IL1B and Kawasaki disease.