Based on the result of multivariate Cox regression, a nomogram integrated the expression of ARRB1, FNBP1, FZD4, and HERC1 and clinical factors (such as grade and stage) was constructed to predict the probability of 3-, 5- and 10-year OS in NSCLC (Fig. 8A). Here, HERC1 is linked to non-small cell lung carcinoma.