TARDBP and frontotemporal dementia: Subject III:14: onset of an accelerating apathy and inertia at the age of 67 years. Also present with stereotypic behavior and disinhibition and therefore fulfils clinical criteria for behavioral variant FTD [30]. There was no clinical suspicion of motor neuron disease or parkinsonian disorder at any time in the disease course. The patient died at an age of 71 years. Immunohistochemistry for TDP-43 and pTDP-43 showed superficially located neurons with intracytoplasmic inclusions.