MMP8 and metastatic malignant neoplasm in the lymph nodes: (Decock et al., 2008; Decock et al., 2011; Korpi et al., 2008) For instance, in breast cancer, elevated plasma levels of MMP‐8 seem to have a protective effect against lymph node metastasis, (Åström et al., 2017) and squamous cell carcinoma of the tongue, in which high‐tumor MMP‐8 expression had associations with improved cancer‐specific survival.