First, the expression of Dcf1 was explored, and the results showed that Dcf1 was downregulated in glioblastoma tissue compared to normal tissue in mRNA and protein (Figure S1A,B), it is consent with data from the gene microarray database (GDS2853, GSE12305; Figure S1C), which implies that the expression level is negatively related to tumor malignancy. Here, TMEM59 is linked to neoplasm.