Although the OAS1 promoter did not directly overlap COVID-19-risk variants, we found several fine-mapped34,35 COVID-19-risk variants, associated with OAS1 expression (eQTLs) (Supplementary Data 6), directly overlapped an intergenic transposase-accessible and H3K27ac-enriched peak region, located 20 kb away from OAS1 promoter (Fig. 2d). This evidence concerns the gene OAS1 and COVID-19.