Decreased baseline BRSK2 CpG3, CpG4, and CpG5 methylation levels were significant predictors of increased PTSD symptom scores at 3-months (CpG3 ß = −0.39, p < 0.001, CpG4 ß = −0.33, p = 0.005, CpG5 ß = −0.27, p = 0.009) and 6-months (CpG3 ß = −0.49, p < 0.001, CpG4 ß = −0.44, p < 0.001, CpG5 ß = −0.38, p < 0.001) post-rape. This evidence concerns the gene BRSK2 and post-traumatic stress disorder.