In PCa cells, the full-length TCF7, TCF7L1, and TCF7L2 complementary (c)DNAs were transiently transfected into LNCaP cells and analyzed for CXCR2, IL-8, and NE markers (chromogranin A (CHGA), chromogranin B (CHGB), synaptophysin (SYP), and enolase 2 (ENO2)). Here, CXCL8 is linked to posterior cortical atrophy.