The survival curve of TP53 Mutation/GU−like group was more closely resembles that of TP53 Wild/GU−like group but not that similar to the TP53 Mutation/GS−like group, indicating that GILncSig rather TP53 mutation was more closely associated with the overall survival of HCC patients, suggesting TP53 mutation status alone does not perform well for predicting outcome of GU−like patients. This evidence concerns the gene TP53 and hepatocellular carcinoma.