MACC1 and neoplasm: For example, the hypermethylated m6A in circEEFSEC and circUBXN7 resulted in the gain of coexpression of circEEFSEC-MACC1 (r = 0.74, P = 4.2e−5) and circUBXN7-KDR (r = 0.71, P = 0.0095) in tumor samples and while there was no correlation between circEEFSEC and MACC1 (r = 0.3, P = 0.34) and between circUBXN7 and KDR (r = 0.25, P = 0.53) in normal samples.