In addition to these effector cells, dendritic cells (DC) (CD11c+MHCII+) and MHCII+ M1 type macrophages relative to CD206+ M2 type macrophages (CD11b+GR-1−F4/80+) (but not the frequency of total macrophages) in the tumor of Prdm1fl/flFoxp3YFP-Cre mice were increased compared to WT mice (Fig. 2f,g and Additional file 6a). Here, ITGAM is linked to neoplasm.