Statistical analysis of three groups revealed that there were differences in neither the presence of gallstones (TP53 mutant vs. TP53 normal vs. CNV group: 33.3% vs. 50% vs. 57.1%, p = 0.51) nor the history of smoking (TP53 mutant vs. TP53 normal vs. CNV group: 10% vs. 16.7% vs. 28.6%, p = 0.61), whereas the coexistence rate of PBM was higher in the TP53 mutation group than in other groups (TP53 mutant vs. TP53 normal vs. CNV group: 60% vs. 20% vs. 0%, p = 0.027). The gene discussed is TP53; the disease is gallstones.