Drug dosage can be recommended according to the metabolism of CYP2D6. A previous study of atorvastatin in the treatment of ischemic stroke found that the G allele of rs1065852 (CYP2D6) had a better lipid-lowering effect, and patiebts carrying the GG genotype had a better effect on atorvastatin treatment reaction. This evidence concerns the gene CYP2D6 and ischemic stroke.