By contrast, a Chinese study of 217 patients with IBD (76 UC and 141 Crohn's disease) found that peripheral blood monocyte count did not significantly differ between active-stage and inactive-stage IBD, regardless of Clostridioides difficile infection, although a positive relationship between peripheral blood monocyte count and CRP was observed in patients with active UC (15). This evidence concerns the gene CRP and Crohn disease.