H2BC5 and cervical carcinoma: LncRNA DCST1-AS1 promoted cell proliferation and invasion, inhibited apoptosis and autophagy by modulating the AKT/mTOR signaling cascade.[26] High expression of the HIST1H2BD was significantly correlated with the prognosis of cervical cancer patients.[27] H2A/H2B plays important roles in processes on the chromatin that allow for transcription, DNA replication, and DNA repair.