PANX1 was shown to be highly expressed in the vast majority of tumors in the Oncomine database, including breast cancer, cervical cancer, colorectal cancer, esophageal cancer (ESCA), gastric cancer, head and neck cancer, kidney cancer, lymphoma, leukemia, lung cancer, pancreatic cancer, and sarcoma. The gene discussed is PANX1; the disease is familial pancreatic carcinoma.