Moreover, JQ1 can specifically downregulate the expression of PD‐L1 on the surface of tumor cells to combat the immune tolerance induced by PDT (Figure 4c–f).[49] Wang and co‐workers reported a type of liposome loaded with an IDO inhibitor (NLG‐8189), which can be activated by the redox of a phospholipid–porphyrin conjugate. The gene discussed is CD274; the disease is neoplasm.