On the other hand, the Rho GTPase pathway, Wnt pathway, G‐protein pathway, and P53 pathway were affected following FMNL2 knockdown, indicating that circHIPK3/miR‐1207‐5p/FMNL2 orchestrating multiple pathways may mediate the tumorigenesis of CRC.85, 86, 87. Here, FMNL2 is linked to colorectal carcinoma.