Since STAT3 is involved in inducing cancer‐related genes and physically and functionally interacting with other tumor transcription factors, silibinin‐loaded MBG nanoparticles were suggested as a novel and effective agent for safe breast cancer chemotherapy.[34] A schematic illustration of some possible therapeutic effects of MBGs combined with ions and chemotherapy agents is shown in Figure 20. Here, STAT3 is linked to neoplasm.