ERBB2 and neoplasm: The addition of contrast agents to OCT increases sensitivity, extending the capabilities into molecular imaging[366] allowing for improved microvascular imaging[367-369], investigation of the fundamental behaviors of tumor associated macrophages and other leukocytes through speckle-modulating OCT[370] as well as the human epidermal growth factor receptor 2 (HER2 neu) protein with magnetomotive OCT which uses antibody conjugated magnetic nanoparticles[371].