Moreover, we observed all annotated glycerophospholipid showed significant depletion in MD-CAD when compared with other two CAD groups (ND-CAD and HD-CAD) (Figure 2A), including phosphatidylinositol [PI, such as PI (18:1/22:6) (LPN207) and PI (20:4/18:0) (LPN208)], phosphatidylcholine [PC, such as PC (18:3/20:5) (LPP1438)], phosphatidylserine [PS, such as PS (22:1/22:6) (LPP 1453), PS (22:4/22:5) (LPP1458), PS (22:0/22:1) (LPP863), PS (22:0/22:2) (LPP911), PS (22:0/22:1) (LPP863), PS (20:0/22:2) (LPP960), PS (20:0/22:1) (LPP932), and PS (22:0/22:2) (LPP960)]. The gene discussed is PRB2; the disease is coronary artery disorder.