We previously observed that recent UVR was positively correlated with CD45RA−/CD27− activated Tregs, CLA+ and CCR4hi Tregs in a cross-sectional analysis of baseline samples from a subset of skin cancer screening patients participating in a prospective cohort study of skin cancer in Tampa, FL, the Viruses in Skin Cancer (VIRUSCAN) Study (29). Here, SELPLG is linked to skin neoplasm.