The study aims were: (1) to evaluate the levels of inflammatory cytokines (tumor necrosis factor alpha (TNF-α), interleukin 1 beta (IL-1β), interleukin 6 (IL-6), interleukin 8 (IL-8), and interleukin 10 (IL-10) in OSA and healthy pregnant women who were homogeneous in age, and body mass index (BMI) in the third trimester; (2) to relate systemic inflammation with adverse maternal and fetal outcomes. This evidence concerns the gene IL6 and obstructive sleep apnea syndrome.