An example of the latter entity is IMD28 (immunodeficiency 28, mycobacteriosis, autosomal recessive; MIM#614889), which results from pathogenic variants of IFNGR2 (interferon-gamma receptor 2; MIM#147569), such as c.123C>G, p.Tyr41* (4). Here, IFNGR2 is linked to mycobacterial infectious disease.