Previous studies have identified biomarkers, such as Alpha-fetoprotein (AFP), apyrimidinic endodeoxyribonuclease 1 (APEX1), glypican 3 (GPC3), Golgi protein-73 (GP73), and Dickkopf-1 (DKK1), for HCC diagnosis (9–13). This evidence concerns the gene GPC3 and hepatocellular carcinoma.