On referring to the HNSCC whole exome data of these 114 genes from TCGA database we found that only 8 of them were a part of the Cancer Gene Census of which only 3 genes, AKT1, LRP1B, and SPECC1 showed a significant difference in survival from the TCGA whole exome data associated with these genes (Figure 8A). Here, SPECC1 is linked to cancer.