The average tumor volumes of different groups were 1834.65 ± 235.42 mm3 (HT29, DMSO), 2173.48 ± 295.34 mm3 (HT29/Nrf3, DMSO), 972.15 ± 235.65 mm3 (HT29/Nrf3, 5-FU), and 1198.21 ± 205.48 mm3 (HT29, 5-FU) (Figure 6(a)). The gene discussed is NFE2L3; the disease is neoplasm.