CDK1 and neoplasm: As expected, the regulation of G2/M checkpoint by CDK1 gene (Cyclin-Dependent Kinase 1) was identified as an essential factor in multiple tumor progressions (Sedlacek et al., 1996; Damiens and Meijer, 2000; Knudsen and Witkiewicz, 2017; Chung et al., 2019).