Notably, blockade of other chemokine receptors in the CC family by their antagonists, e.g., CCR1 - J113863 (27), CCR2 - RS504393 (29), CCR4 - C021 (50), and CCR5 - maraviroc (31, 61), beneficially modulates the changes observed during neuropathy, consistent with our previous reports (27, 29, 50). The gene discussed is CCR4; the disease is neuropathy.