The expressions of RIPK2, RBCK1, TRAFD1, SOD2, NMI, MT2A, CD86, and CD74 were significantly increased in the advanced stages of ccRCC, and the expressions of RIPK2, RBCK1, NOD1, and CDKN1A were significantly increased in the advanced stages of pRCC. Here, NMI is linked to nonpapillary renal cell carcinoma.