The results showed that α-SMA and Col1a1 mRNA levels were significantly increased in the DSS + HF group (α-SMA: DSS + HF vs. chow; p < 0.01, DSS + HF vs. HF; p < 0.05) (Col1a1: DSS + HF vs. chow; p < 0.05, DSS + HF vs. HF; p < 0.01; Figure 1C). This evidence concerns the gene COL1A1 and hydrops fetalis.